Search results for "Intracellular sodium"

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Influence of intracellular sodium concentration on calcium influx in isolated guinea pig auricles.

1969

PharmacologyIntracellular sodiumCalcium metabolismCalcium IsotopesChemistryMyocardiumPharmacology toxicologyGuinea PigsSodiumBiological Transport ActiveGeneral MedicinePharmacologyIn Vitro TechniquesIsotopes of calciumGuinea pigAnimalsCalciumIsotonic SolutionsHeart AtriaIsotonic SolutionsCalcium influxHeart atriumNaunyn-Schmiedebergs Archiv fur Pharmakologie
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Red blood cell sodium and potassium after hydrochlorothiazide.

1981

In six of seven healthy males 6 days of hydrochlorothiazide (HCT), 50 mg twice daily, without potassium supplements resulted in a rise in red blood cell (RBC) sodium concentration. Serum potassium concentration fell in all subjects. Four days after discontinuing HCT, intracellular sodium and extracellular potassium concentrations had normalized. Throughout the evaluation period the course of mean relative intracellular sodium was almost a mirror image of mean relative extracellular potassium. Thus, either the decline of serum potassium or of HCT (because of its inhibitory effect on Na-K-ATPase activity) might have diminished Na-K-ATPase–dependent active RBC sodium efflux with a resultant ri…

PharmacologyIntracellular sodiumMaleErythrocytesTime FactorsPotassiumSodiumSodiumchemistry.chemical_elementPharmacologyRed blood cellHydrochlorothiazidemedicine.anatomical_structureHydrochlorothiazidechemistrySerum potassiummedicinePotassiumHumansPharmacology (medical)EffluxInhibitory effectmedicine.drugClinical pharmacology and therapeutics
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